DBS Think Tank IX was held on August 25–27, 2021 in Orlando FL with US based participants largely in person and overseas participants joining by video conferencing technology. The DBS Think Tank was founded in 2012 and provides an open platform where clinicians, engineers and researchers can freely discuss current and emerging deep brain stimulation technologies as well as the logistical and ethical issues facing the field. The consensus among the DBS Think Tank IX speakers was that DBS expanded in (...) its scope and has been applied to multiple brain disorders in an effort to modulate neural circuitry. After collectively sharing our experiences, it was estimated that globally more than 230,000 DBS devices have been implanted for neurological and neuropsychiatric disorders. As such, this year’s meeting was focused on advances in the following areas: neuromodulation in Europe, Asia and Australia; cutting-edge technologies, neuroethics, interventional psychiatry, adaptive DBS, neuromodulation for pain, network neuromodulation for epilepsy and neuromodulation for traumatic brain injury. (shrink)

SummaryThe present analysis compares the distribution of surnames by means of spatial autocorrelation analysis in the Spain–Portugal border region. The Spanish National Institute of Statistics provides a database of surnames of residents in the western Spanish provinces of Zamora, Salamanca, Cáceres, Badajoz and Huelva. The Spanish and Portuguese patterns of surname distribution were established according to various geographic axes. The results obtained show a low diversity of surnames in this region – especially in the centre – which can be (...) explained by the absence of any major geographic barriers, with the exception of the mountain ranges between hydrographic basins, and by the presence of traditional roads that have existed since Roman times. The latter have resulted in a constant migratory flow over short–median distances, which, as can be deduced from the surnames, fits two north/south territorial axes running parallel to the border between Spain and Portugal. The distribution patterns of Portuguese and Spanish surnames differ with regard to their frequencies in the five provinces studied, which can be attributed to their respective historical, economic and social conditions. It is concluded that the border delimiting these two countries has affected the migratory flow, thereby conditioning the demographic and genetic structure of the western Spanish regions. (shrink)

IntroductionBisphenol A is highly debated and studied in relation to a variety of health outcomes. This large variation in the literature makes BPA a topic that is prone to selective use of literature, in order to underpin one’s own findings and opinion. Over time, selective use of literature, by means of citations, can lead to a skewed knowledge development and a biased scientific consensus. In this study, we assess which factors drive citation and whether this results in the overrepresentation of (...) harmful health effects of BPA.MethodsA citation network analysis was performed to test various determinants of citation. A systematic search identified all relevant publications on the human health effect of BPA. Data were extracted on potential determinants of selective citation, such as study outcome, study design, sample size, journal impact factor, authority of the author, self-citation, and funding source. We applied random effect logistic regression to assess whether these determinants influence the likelihood of citation.ResultsOne hundred sixty-nine publications on BPA were identified, with 12,432 potential citation pathways of which 808 citations occurred. The network consisted of 63 cross-sectional studies, 34 cohort studies, 29 case-control studies, 35 narrative reviews, and 8 systematic reviews. Positive studies have a 1.5 times greater chance of being cited compared to negative studies. Additionally, the authority of the author and self-citation are consistently found to be positively associated with the likelihood of being cited. Overall, the network seems to be highly influenced by two highly cited publications, whereas 60 out of 169 publications received no citations.ConclusionIn the literature on BPA, citation is mostly driven by positive study outcome and author-related factors, such as high authority within the network. Interpreting the impact of these factors and the big influence of a few highly cited publications, it can be questioned to which extent the knowledge development in human literature on BPA is actually evidence-based. (shrink)

The scientist's decision of accepting a given proposition is assumed to be dependent on two factors: the scientist's 'private' information about the value of that statement and the proportion of colleagues who also accept it. This interdependence is modelled in an economic fashion, and it is shown that it may lead to multiple equilibria. The main conclusions are that the evolution of scientific knowledge can be path, dependent, that scientific revolutions can be due to very small changes in the empirical (...) evidence, and that not all possible equilibria are necessarily efficient, neither in the economic nor in the epistemic sense. These inefficiencies, however, can be eliminated if scientists can form coalitions. (shrink)

The purpose of this essay is to investigate and critically analyse some of the formative factors which led to the spiritual maturation of a leading Vīraśaiva saint, Basava. This inquiry focuses on a single event in the life of this great reformer of medieval times, i.e. his spiritual conflict leading to his rejection of the upanayana ceremony. The study will proceed through an investigation of the earliest and subsequent sources which veil the personality of Basava. The traditional view will be (...) challenged as one-sided. By critically comparing the sources, a more comprehensive and plausible account will be suggested. (shrink)

Moulines’ arguments against several types of realism in his book Pluralidad y recursion are considered and a defence of scientific realism consistent with structuralism is offered as a plausible answer to Moulines’ criticisms.

The process of scientific investigation is reconstructed as a process of empirical approximation to the truth. This last concept is explicated as a combination of “degree of simmilarity between theory A and the strongest accepted empirical law at moment t” and the “degree of depth of this empirical law”. A number of methodological theorems are proved, and avision of science closer to sophisticated falsificationism is mathematically deduced from our definitions.

In this paper, an attempt is made to solve various problems posed to current theories of verisimilitude: the problem of linguistic variance; the problem of which are the best scientific methods for getting the most verisimilar theories; and the question of the ontological commitment in scientific theories. As a result of my solution to these problems, and with the help of other considerations of epistemological character, I conclude that the notion of 'Tarskian truth' is dispensable in a rational interpretation of (...) the scientific enterprise. As a logical result, however, falsificationism will be vindicated. (shrink)

The connection between scientific knowledge and our empirical access to realityis not well explained within the structuralist approach to scientific theories. I arguethat this is due to the use of a semantics not rich enough from the philosophical pointof view. My proposal is to employ Sellars–Brandom's inferential semantics to understand how can scientific terms have empirical content, and Hintikka's game-theoretical semantics to analyse how can theories be empirically tested. The main conclusions are that scientific concepts gain their meaning through `basic (...) theories' grounded on `common sense, and that scientific method usually allows the pragmatic verification and falsification of scientific theories. (shrink)

I.—It is a thesis of Christian philosophy that God can bring about anything that does not involve a contradiction in terms. Now a contradietion in terms is denned with reference to an identical proposition. An identical proposition is one in which the predicate is the same as the subject. This is brought about in two ways: one when the predicate is completely identical with the subject, as when you say, ‘A dog is a dog’: two when the predicate is partly (...) identical with the subject as when you say, ‘A black dog is black’, or ‘A dog is an animal’. In both these cases, especially in the latter, it is said that the predicate is included in the idea, or concept or ratio of the subject. If any of these propositions is denied, then you get a simultaneous affirmation and denial of the same thing, of dog, of black, and of animal, respectively, thus producing a contradiction in terms. And not even God can make such propositions true. (shrink)

WE wish to call into question the basic objection to the generic status of being: and here we mean by ‘being’, not the act of existence, but essence. It is objected that whereas being contains all its differences, the genus does not do so. This objection is unsupported by the evidence and therefore fails. A concomitant objection that being is analogical and that the genus is univocal also fails, since the genus is itself analogical. The strange thing is that St. (...) Thomas agrees that the genus contains its differences and that it is analogical; yet Thomists deny that being is a genus. St. Thomas compares the relation of being to the categories with that of the genus to the species. He says that the difference is not outside the genus, but is rather a determination of it. He says that the genus is equivocal, not purely so but as being analogical. It is evident, therefore, from what he says, that being as meaning essence, is the supreme genus. (shrink)

An epistemic notion of verisimilitude (as the 'degree in which a theory seems closer to the full truth to a scientific community') is defined in several ways. Application to the structuralist description of theories is carried out by introducing a notion of 'empirical regularity' in structuralist terms. It is argued that these definitions of verisimilitude can be used to give formal reconstructions of scientific methodologies such as falsificationism, conventionalism and normal science.

Scientists can choose different claims as interpretations of the results of their research. Scientific rhetoric is understood as the attempt to make those claims most beneficial for the scientists' interests. A rational choice, game-theoretic model is developed to analyze how this choice can be made and to assess it from a normative point of view. The main conclusion is that `social' interests (pursuit of recognition) may conflict with `cognitive' ones when no constraints are put on the choices of the authors (...) of scientific papers, as in an `ideal free speech situation'. Scientific institutions may help to solve this conflict. Lastly, some empirical predictions are offered that can inspire future social research of the refereeing process. (shrink)

The doctrine of double effect (DOE) has its origins in Roman Catholic thought and has been held to have widespread applications in bioethics. Its applications range over issues of maternal-fetal conflict, organ donation and transplant, euthanasia, and resource allocation, among other controversial issues. Recently, Joseph Boyle, the foremost proponent of the DOE over the past few decades, has argued that the DOE is required by the absolutist context of the Catholic tradition, and, further, that anyone who rejects this particular context (...) is not entitled to use the doctrine. In this essay, I will focus exclusively on the intention condition of the DOE and its central distinction, i.e., intention/side effect. I will proceed by considering in turn (1) Boyle's argument that the absolutist moral framework of the Catholic tradition requires the intention/side effect distinction; (2) the ways in which that framework is made vulnerable by this requirement; and (3) just why the DOE should be viable even outside of the Catholic tradition if it turns out that a feature of (l) is correct and the challenges of (2) can be met. (shrink)

National consciousness, which is primarily a deep awareness of one or another people of its ethnic isolation and originality of historical destiny, is formed under the influence of various objective and subjective factors. Depending on which nationalistic factors are bestowed, distinguish the objectivist and subjectivist theory of the nation.

Zoologist A. J. Cain began historical research on Linnaeus in 1956 in connection with his dissatisfaction over the standard taxonomic hierarchy and the rules of binomial nomenclature. His famous 1958 paper 'Logic and Memory in Linnaeus's System of Taxonomy' argues that Linnaeus was following Aristotle's method of logical division without appreciating that it properly applies only to 'analysed entities' such as geometric figures whose essential nature is already fully known. The essence of living things being unanalysed, there is no basis (...) on which to choose the right characters to define a genus nor on which to differentiate species. Yet Cain 's understanding of Aristotle, which depended on a 1916 text by H. W. B. Joseph, was fatally flawed. In the 1990s Cain devoted himself to further historical study and softened his verdict on Linnaeus, praising his empiricism. The idea that Linnaeus was applying an ancient and inappropriate method cries out for fresh study and revision. (shrink)